Background: Often accompanying comorbidity in patients with heart failure and overweight isare sleep disorders. Detection and treatment of sleep apnea will be helpful in these patients.
Purpose: To determine the phenotypic characteristics of sleep apnea in these patients. To determine whether there is a link between forms of sleep apnea and type of heart failure.
Methods: Hospitalized 46 patients with acute and exacerbateexacerbated heart failure. MeasuringMeasurement of NT proBNP. Sleep apnea screening with ApneaLinkTM. Echocardiographic assessment of left ventricular ejection fraction (LVEF) and the E/e‘ ratio. Statistical methods to compare independent samples and correlation analysis for linear dependence.
Results: We hospitalized the 46 overweight patients with acute and exacerbated chronic heart failure,; sleep apnea was diagnosed in 36 patients (78.2%). Of these, 83.3% (n=30) havehad оbstructive sleep apnea (OSA) and 16.7% (n=6) havehad central sleep apnea (CSA). There was a statistically significant difference in LVEF for the group with CSA (n=6) vs group with OSA (n=30) (41.67±13.88 vs. 50.57±8.16, p=0.038). For diastolic function didn'tdid not reach statistical significance for E/e' ratio (20,33±5,00 vs. 17,06±4,02, p=0,089). Regarding NTproBNP, there iswas no significant difference between the groups with OSA and those with CSA (2978.5±2664.1 vs. 2063.36±1877.27 pg/ml, p=0.316). There iswas a moderate negative correlation with LVEF and number of central sleep apnea events (r=-0,334, p=0,047).
Conclusions: With greater frequencyObstructive sleep apnea occurs obstructive sleep apneawith greater frequency. Left ventricular systolic function iswas lower in patients with central sleep apnea. There iswas a reverse correlation between ejection fraction and number of central apnea.
The text above was approved for publishing by the original author.
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